Scientists have made remarkable progress over the past few decades in biological imaging, from the atomic scale (subnanometer) to the cellular (micron) scale. There are extraordinary opportunities for scientists working to understand and harness biological systems for addressing mission-relevant challenges of the U.S. Department of Energy’s (DOE) Office of Biological and Environmental Research (BER). Many of these advances are made possible by BER structural biology resources that support unique crystallography, scattering,  spectroscopy, and imaging capabilities available at national neutron and light source user facilities operated by DOE’s Office of Basic Energy Sciences. more…

Highlights

Dynamic Regulation of Histone Chaperone Nucleoplasmin May 3, 2018

“Zip-code” Mechanism for Hormone Signaling Revealed January 25, 2018

Structure of a Flavoenzyme Assembly Intermediate January 18, 2018

A Regional Model for Uranium Redox and Mobility December 15, 2017

Cyanobacterial Studies Examine Cellular Structure During Nitrogen Starvation November 15, 2017

Dynamics on Cellulose Show Two Important Populations from Neutron Scattering and Simulations September 19, 2017

Measuring and Modeling Poplar Root Water Extraction After Drought Using Neutron Imaging September 9, 2017

The Origins of Photosynthesis in a Sun-Loving Bacteria September 8, 2017

Exploring the Roots of Photosynthesis in a Soil-Dwelling Bacterium September 8, 2017

X-ray Footprinting Solves Mystery of Metal-Breathing Protein August 14, 2017

Hacking the Bacterial Social Network August 11, 2017

New Chemical Strategy for Conversion of CO2 to Biomass August 3, 2017

The CRISPR Target-Recognition Mechanism July 20, 2017

Brown Rot Fungi Reveal a New Approach for Biomass Conversion to Fuels and Chemicals July 11, 2017

Novel Orange Carotenoid Proteins Shedding Light on Evolution of Cyanobacteria Photoprotection July 10, 2017

Finding New Clues to a Common Respiratory Virus June 30, 2017

Pulling the Tablecloth Out from Under Essential Metabolism June 26, 2017

Revealing a Peanut Family Secret for Making Chemical Building Blocks June 26, 2017

Revealing How Bacterial Organelles Assemble June 23, 2017

Study on Human Skin Microbiome Finds Archaea Abundance Associated with Age June 22, 2017

Engineering Better Plant Cultivars for Iron Uptake by Modifying the Fe Deficiency Response in Arabidopsis thaliana June 16, 2017

Using Neutrons to Resolve Plasma Membrane Organization in Living Bacterial Cells May 23, 2017

Probing S-layer Protein Structural Dynamics by SAXS May 9, 2017

Could This Enzyme Help Turn Biofuel Waste into Something Useful? April 18, 2017

Sequencing of Green Alga Genome Provides Blueprint to Advance Clean Energy, Bioproducts April 12, 2017

Direct Measurement of Protein Dynamics In Vivo April 7, 2017

Ebola Virus January 22, 2017

Neutrons Identify Oxygen Activation in LPMOs December 22, 2016

Detailing the Molecular Roots of Alzheimer’s Disease December 20, 2016

Hollow Pyramid Unlocks Principles of Protein Architecture December 14, 2016

Crystal Structure of NOV1 December 12, 2016

Designing Cyclic Oligomers: Greater than the Sum of Their Parts December 5, 2016

Mapping the Migration of Genetic Material November 15, 2016

Investigating Ptychography of a Bacterium’s Inner Compass November 15, 2016

Description of Hydration Water in Green Fluorescent Protein Solution October 6, 2016

How Your Body Transports Zinc to Protect Your Health August 15, 2016

Cellulose Synthesis Complex January 12, 2016

Finding Manganese Reduction-Oxidation Drives Plant Debris Decomposition September 22, 2015

Modular Construction on a Biomolecular Scale August 25, 2015

BAP Protein June 10, 2015

Protein Cage November 19, 2014

Understanding Nitrogen Fixation in Bacteria September 26, 2014

Biomass Deconstruction January 12, 2014

Spatial Organization of Lipid Domains in a Biomimetic Four-Lipid System May 8, 2013

Major Scaffold Component in Nuclear Pore Complex April 2, 2013

X-rays and Protein Crystal Samples January 3, 2013

Watching the Evolution of a Protein’s Function December 9, 2012

Comparison of GH3 Protein Binding Sites May 24, 2012