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YearReferenceFacilitiesTechniques
2020Banda, D.M., Pereira, J.H., Liu, A.K.A et al., Novel bacterial clade reveals origin of form I Rubisco. Nature Plants 6 1158—1166 DOI: 10.1038/s41477-020-00762-4 (related highlight) (feature story)ALSX-Ray Macromolecular Crystallography (MC),Small-Angle X-Ray Scattering (SAXS)Banda, D.M., Pereira, J.H., Liu, A.K.A et al. Novel bacterial clade reveals origin of form I RubiscoNature Plants6 1158—116610.1038/s41477-020-00762-4
2020Chen Z., R. D. Kibler, A. Hunt, F. Busch, J. Pearl, and M. Jia. De novo design of protein logic gates. Science 368(6486)78-84 DOI: 10.1126/science.aay2790ALSSmall-Angle X-Ray ScatteringChen Z., R. D. Kibler, A. Hunt, F. Busch, J. Pearl, and M. JiaDe novo design of protein logic gatesScience368(6486)78-8410.1126/science.aay2790
2020Hutchison, J.M., K.-C. Shih, H. A. Scheidt, S. M. Fantin, et al.. Bicelles rich in both sphingolipids and cholesterol and their use in studies of membrane proteins. Journal of the American Chemical Society 142, 12715—12729 DOI: 10.1021/jacs.0c04669 (related highlight) (feature story)NSLSII,SNS-HFIRSmall-Angle X-Ray Scattering (SAXS),Small-Angle Neutron Scattering (SANS)Hutchison, J.M., K.-C. Shih, H. A. Scheidt, S. M. Fantin, et al.Bicelles rich in both sphingolipids and cholesterol and their use in studies of membrane proteinsJournal of the American Chemical Society142, 12715-1272910.1021/jacs.0c04669
2020Pinals R. L., D. Yang, D. J. Rosenberg, T. Chaudhary, A. R. Crothers, Dr. A. T. Iavarone, Dr. M. Hammel and Prof. M. P. Landry. Quantitative Protein Corona Composition and Dynamics on Carbon Nanotubes in Biological Environments. Angewandte Chemie International Edition 1433-7851 DOI: 10.1002/anie.202008175ALS Small-Angle X-Ray ScatteringPinals R. L., D. Yang, D. J. Rosenberg, T. Chaudhary, A. R. Crothers, Dr. A. T. Iavarone, Dr. M. Hammel and Prof. M. P. LandryQuantitative Protein Corona Composition and Dynamics on Carbon Nanotubes in Biological EnvironmentsAngewandte Chemie International Edition1433-785110.1002/anie.202008175
2020Pingali, S. V., Smith, M. D., S.-H. Liu, T. B. Rawal, et al.. Deconstruction of biomass enabled by local demixing of cosolvents at cellulose and lignin surfaces. PNAS 17(29), 16776—16781 DOI: 10.1073/pnas.1922883117 (related highlight) (feature story)SNS-HFIRSmall-Angle Neutron Scattering (SANS)Pingali, S. V., Smith, M. D., S.-H. Liu, T. B. Rawal, et al.Deconstruction of biomass enabled by local demixing of cosolvents at cellulose and lignin surfacesPNAS17(29), 16776–1678110.1073/pnas.1922883117
2020Ueda G., A. Antanasijevic, J. A Fallas, W. Sheffler, J. Copps, D. Ellis, G. B. Hutchinson, A. Moyer and A. Yasmeen. Tailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigens. eLife 9e57659 DOI: 10.7554/eLife.57659ALSSmall-Angle X-Ray ScatteringUeda G., A. Antanasijevic, J. A Fallas, W. Sheffler, J. Copps, D. Ellis, G. B. Hutchinson, A. Moyer and A. YasmeenTailored design of protein nanoparticle scaffolds for multivalent presentation of viral glycoprotein antigenseLife9e5765910.7554/eLife.57659
2019Boatman, E.M., M. B. Goodwin, H. N. Holman, et al. Mechanisms of soft tissue and protein preservation in Tyrannosaurus rex. Scientific Reports  9, 15678. DOI: 10.1038/s41598-019-51680-1 (feature story)ALSInfrared (IR) ImagingBoatman, E.M., M. B. Goodwin, H. N. Holman, et alMechanisms of soft tissue and protein preservation in Tyrannosaurus rexScientific Reports 9, 15678.10.1038/s41598-019-51680-1
2019Buller, A. R., P. van Roye, J. K. B. Cahn, R. A. Scheele, M. Herger, and F. H. Arnold. Directed evolution mimics allosteric activation by stepwise tuning of the conformational ensemble. Journal of the American Chemical Society 140(23), 7256—66 DOI: 10.1021/jacs.8b03490 (related highlight)SSRLX-Ray Macromolecular Crystallography (MC)Buller, A. R., P. van Roye, J. K. B. Cahn, R. A. Scheele, M. Herger, and F. H. ArnoldDirected evolution mimics allosteric activation by stepwise tuning of the conformational ensembleJournal of the American Chemical Society140(23), 7256—6610.1021/jacs.8b03490
2019Chang, C., C. Brooke, H. Piao, J. Mack, G. Babnigg, A. Joachimiak, and M. Hess. A 2.08 A resolution structure of HLB5, a novel cellulase from the anaerobic gut bacterium Parabacteroides johnsonii DSM 18315. Protein Sci 28(4)794-799 DOI: 10.1002/pro.3582APSX-Ray Macromolecular CrystallographyChang, C., C. Brooke, H. Piao, J. Mack, G. Babnigg, A. Joachimiak, and M. HessA 2.08 A resolution structure of HLB5, a novel cellulase from the anaerobic gut bacterium Parabacteroides johnsonii DSM 18315Protein Sci28(4)794-79910.1002/pro.3582
2019Chundawat, S. P. S., L. D. Sousa, S. Roy, Z. Yang, S. Gupta, R. Pal, C. Zhao, S.-H. Liu, L. Petridis, H. O'Neill, and S. V. Pingali. Ammonia-salt solvent promotes cellulosic biomass deconstruction under ambient pretreatment conditions to enable rapid soluble sugar production at ultra-low enzyme loadings. Green Chemistry  22(1) 204—218 DOI: 10.1039/C9GC03524A (related highlight) (feature story)SNS-HFIRSmall-Angle Neutron Scattering (SANS)Chundawat, S. P. S., L. D. Sousa, S. Roy, Z. Yang, S. Gupta, R. Pal, C. Zhao, S.-H. Liu, L. Petridis, H. O'Neill, and S. V. PingaliAmmonia-salt solvent promotes cellulosic biomass deconstruction under ambient pretreatment conditions to enable rapid soluble sugar production at ultra-low enzyme loadingsGreen Chemistry22(1) 204—21810.1039/C9GC03524A
2019DeMirci, H., Y. Rao, G. M. Stoffel, B. Vögeli,, K. Schell, A. Batyuk, C. Gati, R. G. Sierra, M. S. Hunter, E. Han Dao, H. I. Ciftci, B. Hayes, F. Poitevin, K. Tono, D. A. Saez,  E. Vöhringer-Martinez, S. Deutsch, Y. Yoshikuni, T. J. Erb, and S. Wakatsuki. Coupled inter-subunit dynamics enable the fastest CO2-fixation by reductive carboxylases. bioRxiv preprint DOI: 10.1101/607101 (related highlight)SSRLX-Ray Macromolecular Crystallography (MC)DeMirci, H., Y. Rao, G. M. Stoffel, B. Vögeli, K. Schell, A. Batyuk, C. Gati, R. G. Sierra, M. S. Hunter, E. Han Dao, H. I. Ciftci, B. Hayes, F. Poitevin, K. Tono, D. A. Saez, E. Vöhringer-Martinez, S. Deutsch, Y. Yoshikuni, T. J. Erb, and S. WakatsukiCoupled inter-subunit dynamics enable the fastest CO2-fixation by reductive carboxylasesbioRxiv preprint10.1101/607101
2019Endapally, S., D. Frias, M. Grzemska, A. Gay, D. R. Tomchick, and A. Radhakrishnan. Molecular discrimination between two conformations of sphingomyelin in plasma membranes. Cell 176(5), 1040-1053 DOI: 10.1016/j.cell.2018.12.042 (feature story)APSX-Ray Macromolecular Crystallography (MC)Endapally, S., D. Frias, M. Grzemska, A. Gay, D. R. Tomchick, and A. RadhakrishnanMolecular discrimination between two conformations of sphingomyelin in plasma membranesCell176(5), 1040-105310.1016/j.cell.2018.12.042
2019Guo, G., M.R. Fuchs, W. Shi, J. Skinner, E. Berman, C.M. Ogata, W.A. Hendrickson, Q. McSweeney, and S. Liu. Sample manipulation and data assembly for robust microcrystal synchrotron crystallography. IUCrJ 5(3)238-246 DOI: 10.1107/S2052252518005389 (feature story)NSLSIIX-Ray Macromolecular Crystallography (MC)Guo, G., M.R. Fuchs, W. Shi, J. Skinner, E. Berman, C.M. Ogata, W.A. Hendrickson, Q. McSweeney, and S. LiuSample manipulation and data assembly for robust microcrystal synchrotron crystallographyIUCrJ5(3)238-24610.1107/S2052252518005389
2019Guo, G., P. Zhu, M. R. Fuchs, W. Shi, B. Andi, Y. Gao, W. A. Hendrickson, S. McSweeney, and Q. Li. Synchrotron microcrystal native-SAD phasing at a low energy. IUCrJ 6(4) DOI: 10.1107/S2052252519004536 (feature story)NSLSIIX-Ray Macromolecular Crystallography (MC)Guo, G., P. Zhu, M. R. Fuchs, W. Shi, B. Andi, Y. Gao, W. A. Hendrickson, S. McSweeney, and Q. LiSynchrotron microcrystal native-SAD phasing at a low energyIUCrJ6(4)10.1107/S2052252519004536
2019Hoshika, S., N. A. Leal, M.-J. Kim, M.-S. Kim, N. B. Karalkar, H.-J. Kim, A. M. Bates, N. E. Watkins, H. A. SantaLucia, A. J. Meyer, S. DasGupta, J. A. Piccirilli, A. D. Ellington, J. SantaLucia, M. M. Georgiadis, and S. A. Benner. Hachimoji DNA and RNA A genetic system with eight building blocks. Science 363(6429), 884-887 DOI: 10.1126/science.aat0971 (related highlight)SSRLX-Ray Macromolecular Crystallography (MC)Hoshika, S., N. A. Leal, M.-J. Kim, M.-S. Kim, N. B. Karalkar, H.-J. Kim, A. M. Bates, N. E. Watkins, H. A. SantaLucia, A. J. Meyer, S. DasGupta, J. A. Piccirilli, A. D. Ellington, J. SantaLucia, M. M. Georgiadis, and S. A. BennerHachimoji DNA and RNA A genetic system with eight building blocksScience363(6429), 884-88710.1126/science.aat0971
2019Hu, Y., S. Tain, C. Foyer, D. Fou, H. Wang, W. Zhou, T. Liu, J. Ge, L. Li, and X. Lin. Efficient phloem transport significantly remobilizes cadmium from old to young organs in a hyperaccumulator Sedum alfredii. Journal of Hazardous Materials 365, 421—29 DOI: 10.1016/j.jhazmat.2018.11.034 (related highlight)SSRLX-Ray ImagingHu, Y., S. Tain, C. Foyer, D. Fou, H. Wang, W. Zhou, T. Liu, J. Ge, L. Li, and X. LinEfficient phloem transport significantly remobilizes cadmium from old to young organs in a hyperaccumulator Sedum alfrediiJournal of Hazardous Materials365, 421-2910.1016/j.jhazmat.2018.11.034
2019Lee, S. G., E. Salomon, O. Yu, and J. M. Jez. 2019. Molecular basis for branched steviol glucoside biosynthesis. Proceedings of the National Academies USA 116(26), 13131-13136 DOI: 10.1073/pnas.1902104116 (feature story)APSX-Ray Macromolecular Crystallography (MC)Lee, S. G., E. Salomon, O. Yu, and J. M. Jez. 2019Molecular basis for branched steviol glucoside biosynthesisProceedings of the National Academies USA116(26), 13131-1313610.1073/pnas.1902104116
2019Michalska, K., K. Zhang, Z.M. March, C. Hatzos-Skintges, G. Pintilie, L. Bigelow, L.M. Castellano, L.J. Miles, M.E. Jackrel, E. Chuang, R. Jedrzejczak, J. Shorter, W. Chiu, and A. Joachimiak. Structure of Calcarisporiella thermophila Hsp104 disaggregase that antagonizes diverse proteotoxic misfolding events. Structure 27(3)449-463.e447 DOI: 10.1016/j.str.2018.11.001 (feature story)APSX-Ray Macromolecular Crystallography (MC),Multiscale Imaging (or Hybrid) ApproachesMichalska, K., K. Zhang, Z.M. March, C. Hatzos-Skintges, G. Pintilie, L. Bigelow, L.M. Castellano, L.J. Miles, M.E. Jackrel, E. Chuang, R. Jedrzejczak, J. Shorter, W. Chiu, and A. JoachimiakStructure of Calcarisporiella thermophila Hsp104 disaggregase that antagonizes diverse proteotoxic misfolding eventsStructure27(3)449-463.e44710.1016/j.str.2018.11.001
2019Rittle, J., M. J. Field, M. T. Green, and F. A. Tezcan.  An efficient, step-economical strategy for the design of functional metalloproteins. Nature Chemistry 11, 434-441 DOI: 10.1038/s41557-019-0218-9 (related highlight)SSRLX-Ray Macromolecular Crystallography (MC)Rittle, J., M. J. Field, M. T. Green, and F. A. TezcanAn efficient, step-economical strategy for the design of functional metalloproteinsNature Chemistry11, 434-44110.1038/s41557-019-0218-9
2019Sharma, V.K. and S. Qian. Effect of an Antimicrobial Peptide on Lateral Segregation of Lipids, a Structure and Dynamics Study by Neutron Scattering. Langmuir 35(11) 4152-4160 DOI: 10.1021/acs.langmuir.8b04158 (related highlight)SNS-HFIRSmall-Angle Neutron Scattering (SANS),Neutron SpectroscopySharma, V.K. and S. QianEffect of an Antimicrobial Peptide on Lateral Segregation of Lipids, a Structure and Dynamics Study by Neutron ScatteringLangmuir35(11) 4152-416010.1021/acs.langmuir.8b04158
2019Sierra-Gomez Y., A. Rodriguez-Hernandez, P. Cano-Sanchez, H. Gomez-Velasco, A. Hernandez-Santoyo, D. Siliqi, and A. Rodriguez-Romero. A biophysical and structural study of two chitinases from Agave tequilana and their potential role as defense proteins. FEBS Journal 286, 4778-4796 DOI: 10.1111/febs.14993 (related highlight)SSRLSmall-Angle X-Ray Scattering (SAXS)Sierra-Gomez Y., A. Rodriguez-Hernandez, P. Cano-Sanchez, H. Gomez-Velasco, A. Hernandez-Santoyo, D. Siliqi, and A. Rodriguez-RomeroA biophysical and structural study of two chitinases from Agave tequilana and their potential role as defense proteinsFEBS Journal286, 4778-479610.1111/febs.14993
2019Stingaciu, L.-R., H.M. O'Neill, M. Liberton, H.B. Pakrasi, and V.S. Urban. Influence of Chemically Disrupted Photosynthesis on Cyanobacterial Thylakoid Dynamics in Synechocystis sp. PCC 6803. Scientific Reports 95711 DOI: 10.1038/s41598-019-42024-0 (related highlight)SNS-HFIRNeutron Spectroscopy,Small-Angle Neutron Scattering (SANS)Stingaciu, L.-R., H.M. O'Neill, M. Liberton, H.B. Pakrasi, and V.S. UrbanInfluence of Chemically Disrupted Photosynthesis on Cyanobacterial Thylakoid Dynamics in Synechocystis sp. PCC 6803Scientific Reports9571110.1038/s41598-019-42024-0
2018Chang, C.-Y., X. Yan, I. Crnovcic, T. Annaval, C. Chang, B. Nocek, J.D. Rudolf, D. Yang, Hindra, G. Babnigg, A. Joachimiak, G.N. Phillips, and B. Shen. Resistance to enediyne antitumor antibiotics by sequestration. Cell Chemical Biology 25(9) 1075-1085.e1074 DOI: 10.1016/j.chembiol.2018.05.012 (feature story)APSX-Ray Macromolecular Crystallography (MC)Chang, C.-Y., X. Yan, I. Crnovcic, T. Annaval, C. Chang, B. Nocek, J.D. Rudolf, D. Yang, Hindra, G. Babnigg, A. Joachimiak, G.N. Phillips, and B. ShenResistance to enediyne antitumor antibiotics by sequestrationCell Chemical Biology25(9)1075-1085.e107410.1016/j.chembiol.2018.05.012
2018Hammond, C. M., R. A. Root, R. M.Maier, and J. Chorover. Mechanisms of arsenic sequestration by Prosopis juliflora during the phytostabilization of metalliferous mine tailings. Environmental Science & Technology 52(3), 1156-1164 DOI: 10.1021/acs.est.7b04363 (related highlight)SSRLX-Ray Absorption and Emission Spectroscopy (XAS)Hammond, C. M., R. A. Root, R. M.Maier, and J. ChoroverMechanisms of arsenic sequestration by Prosopis juliflora during the phytostabilization of metalliferous mine tailingsEnvironmental Science & Technology52(3), 1156-116410.1021/acs.est.7b04363
2018Keable, S. M., et al. 2018. Structural characterization of the nitrogenase molybdenum-iron protein with the substrate acetylene trapped near the active site. Journal of Inorganic Chemistry 180, 129-134 DOI: 10.1016/j.jinorgbio.2017.12.008 (related highlight)SSRLX-Ray Macromolecular Crystallography (MC)Keable, S. M., et al. 2018Structural characterization of the nitrogenase molybdenum-iron protein with the substrate acetylene trapped near the active siteJournal of Inorganic Chemistry180, 129–13410.1016/j.jinorgbio.2017.12.008
2018Khandelwal, A., C.N. Kent, M. Balch, S. Peng, S.J. Mishra, J. Deng, V.W. Day, W. Liu, C. Subramanian, M. Cohen, J.M. Holzbeierlein, R. Matts, and B.S.J. Blagg. Structure-guided design of an Hsp90â N-terminal  isoform-selective inhibitor. Nature Communications 9(1)425 DOI: 10.1038/s41467-017-02013-1APSX-Ray Macromolecular Crystallography (MC)Khandelwal, A., C.N. Kent, M. Balch, S. Peng, S.J. Mishra, J. Deng, V.W. Day, W. Liu, C. Subramanian, M. Cohen, J.M. Holzbeierlein, R. Matts, and B.S.J. BlaggStructure-guided design of an Hsp90â N-terminal isoform-selective inhibitorNature Communications9(1)42510.1038/s41467-017-02013-1
2018Lee, S., J. Choi, J. Mohanty, L.P. Sousa, F. Tome, E. Pardon, J. Steyaert, M.A. Lemmon, I. Lax, and J. Schlessinger. Structures of beta-klotho reveal a 'zip code'-like mechanism for endocrine FGF signalling. Nature 553(7689) 501-505 DOI: 10.1038/nature25010 (related highlight)SSRLX-Ray Macromolecular CrystallographyLee, S., J. Choi, J. Mohanty, L.P. Sousa, F. Tome, E. Pardon, J. Steyaert, M.A. Lemmon, I. Lax, and J. SchlessingerStructures of beta-klotho reveal a 'zip code'-like mechanism for endocrine FGF signallingNature553(7689)501-50510.1038/nature25010
2018Lopez, A., S. C. Silva, S. Webb, D. Hesterberg, and D. B. Buchwalter. Periphyton and abiotic factors influencing arsenic speciation in aquatic environments. Environmental Toxicology and Chemistry 37(3), 903-913 DOI: 10.1002/etc.4025 (related highlight)SSRLX-Ray ImagingLopez, A., S. C. Silva, S. Webb, D. Hesterberg, and D. B. BuchwalterPeriphyton and abiotic factors influencing arsenic speciation in aquatic environmentsEnvironmental Toxicology and Chemistry37(3), 903-91310.1002/etc.4025
2018Sharma, P., E. Maklashina, G. Cecchini, and T.M. Iverson. Crystal structure of an assembly intermediate of respiratory Complex II. Nat Commun 9(1) 274 DOI: 10.1038/s41467-017-02713-8 (related highlight)SSRLSmall-Angle X-Ray Scattering (SAXS)Sharma, P., E. Maklashina, G. Cecchini, and T.M. IversonCrystal structure of an assembly intermediate of respiratory Complex IINat Commun9(1)27410.1038/s41467-017-02713-8
2018Subramanian, R.H., S. J. Smith, R. G. Alberstein, J. B. Bailey, L. Zhang, G. Cardone, L. Suominen, M. Chami, H. Stahlberg, T. S. Baker, F. A. Tezcan. Self-assembly of a designed nucleoprotein architecture through multimodal interactions. ACS Central Science 4(11), 1578-1586 DOI: 10.1021/acscentsci.8b00745 (related highlight)SSRLSmall-Angle X-Ray Scattering (SAXS)Subramanian, R.H., S. J. Smith, R. G. Alberstein, J. B. Bailey, L. Zhang, G. Cardone, L. Suominen, M. Chami, H. Stahlberg, T. S. Baker, F. A. TezcanSelf-assembly of a designed nucleoprotein architecture through multimodal interactionsACS Central Science4(11), 1578-158610.1021/acscentsci.8b00745
2018Xu, C., K. Liu, M. Lei, A. Yang, Y. Li, T.R. Hughes, and J. Min. DNA sequence recognition of human CXXC domains and their structural determinants. Structure 26(1)85-95.e83 DOI: 10.1016/j.str.2017.11.022APSX-Ray Macromolecular Crystallography (MC)Xu, C., K. Liu, M. Lei, A. Yang, Y. Li, T.R. Hughes, and J. MinDNA sequence recognition of human CXXC domains and their structural determinantsStructure26(1)85-95.e8310.1016/j.str.2017.11.022
2017Anunciado, D.B., V.P. Nyugen, G.B. Hurst, M.J. Doktycz, V. Urban, P. Langan, E. Mamontov, and H. O'Neill. In vivo protein dynamics on the nanometer length scale and nanosecond time scale. J Phys Chem Lett 8(8)1899-1904 DOI: 10.1021/acs.jpclett.7b00399 (related highlight)SNS-HFIRSmall-Angle X-Ray Scattering (SAXS)Anunciado, D.B., V.P. Nyugen, G.B. Hurst, M.J. Doktycz, V. Urban, P. Langan, E. Mamontov, and H. O'NeillIn vivo protein dynamics on the nanometer length scale and nanosecond time scaleJ Phys Chem Lett8(8)1899-190410.1021/acs.jpclett.7b00399
2017Bao, H., M.R. Melnicki, E.G. Pawlowski, M. Sutter, M. Agostoni, S. Lechno-Yossef, F. Cai, B.L. Montgomery, and C.A. Kerfeld. Additional families of orange carotenoid proteins in the photoprotective system of cyanobacteria. Nat Plants 317089 DOI: 10.1038/nplants.2017.89 (related highlight)ALSX-Ray Macromolecular Crystallography (MC)Bao, H., M.R. Melnicki, E.G. Pawlowski, M. Sutter, M. Agostoni, S. Lechno-Yossef, F. Cai, B.L. Montgomery, and C.A. KerfeldAdditional families of orange carotenoid proteins in the photoprotective system of cyanobacteriaNat Plants31708910.1038/nplants.2017.89
2017Chatterjee, S., P. Luthra, E. Esaulova, E. Agapov, B.C. Yen, D.M. Borek, M.R. Edwards, A. Mittal, D.S. Jordan, P. Ramanan, M.L. Moore, R.V. Pappu, M.J. Holtzman, M.N. Artyomov, C.F. Basler, G.K. Amarasinghe, and D.W. Leung. Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses. Nat Microbiol 217101 DOI: 10.1038/nmicrobiol.2017.101 (related highlight)APSX-Ray Macromolecular Crystallography (MC)Chatterjee, S., P. Luthra, E. Esaulova, E. Agapov, B.C. Yen, D.M. Borek, M.R. Edwards, A. Mittal, D.S. Jordan, P. Ramanan, M.L. Moore, R.V. Pappu, M.J. Holtzman, M.N. Artyomov, C.F. Basler, G.K. Amarasinghe, and D.W. LeungStructural basis for human respiratory syncytial virus NS1-mediated modulation of host responsesNat Microbiol21710110.1038/nmicrobiol.2017.101
2017Dhiman, I., H. Bilheux, K. DeCarlo, S.L. Painter, L. Santodonato, and J.M. Warren. Quantifying root water extraction after drought recovery using sub-mm in situ empirical data. Plant and Soil 424(1-2) 73-89 DOI: 10.1007/s11104-017-3408-5 (related highlight)SNS-HFIRNeutron ImagingDhiman, I., H. Bilheux, K. DeCarlo, S.L. Painter, L. Santodonato, and J.M. WarrenQuantifying root water extraction after drought recovery using sub-mm in situ empirical dataPlant and Soil424(1-2)73-8910.1007/s11104-017-3408-5
2017Fallas, J.A., G. Ueda, W. Sheffler, V. Nguyen, D.E. McNamara, B. Sankaran, J.H. Pereira, F. Parmeggiani, T.J. Brunette, D. Cascio, T.R. Yeates, P. Zwart, and D. Baker. Computational design of self-assembling cyclic protein homo-oligomers. Nat Chem 9(4)353-360 DOI: 10.1038/nchem.2673 (related highlight)ALSSmall-Angle X-Ray Scattering (SAXS)Fallas, J.A., G. Ueda, W. Sheffler, V. Nguyen, D.E. McNamara, B. Sankaran, J.H. Pereira, F. Parmeggiani, T.J. Brunette, D. Cascio, T.R. Yeates, P. Zwart, and D. BakerComputational design of self-assembling cyclic protein homo-oligomersNat Chem9(4)353-36010.1038/nchem.2673
2017Fukushima, T., S. Gupta, B. Rad, J.A. Cornejo, C.J. Petzold, L.J.G. Chan, R.A. Mizrahi, C.Y. Ralston, and C.M. Ajo-Franklin. The Molecular Basis for Binding of an Electron Transfer Protein to a Metal Oxide Surface. J Am Chem Soc 139(36) 12647-12654 DOI: 10.1021/jacs.7b06560 (related highlight)ALSX-Ray Footprinting Mass SpectrometryFukushima, T., S. Gupta, B. Rad, J.A. Cornejo, C.J. Petzold, L.J.G. Chan, R.A. Mizrahi, C.Y. Ralston, and C.M. Ajo-FranklinThe Molecular Basis for Binding of an Electron Transfer Protein to a Metal Oxide SurfaceJ Am Chem Soc139(36)12647-1265410.1021/jacs.7b06560
2017Gisriel, C., I. Sarrou, B. Ferlez, J.H. Golbeck, K.E. Redding, and R. Fromme. Structure of a symmetric photosynthetic reaction center-photosystem. Science 357(6355) 1021-1025 DOI: 10.1126/science.aan5611 (related highlight)ALS, APSX-Ray Macromolecular Crystallography (MC)Gisriel, C., I. Sarrou, B. Ferlez, J.H. Golbeck, K.E. Redding, and R. FrommeStructure of a symmetric photosynthetic reaction center-photosystemScience357(6355)1021-102510.1126/science.aan5611
2017Goodell, B., Y. Zhu, S. Kim, K. Kafle, D. Eastwood, G. Daniel, J. Jellison, M. Yoshida, L. Groom, S.V. Pingali, and H. O'Neill. Modification of the nanostructure of lignocellulose cell walls via a non-enzymatic lignocellulose deconstruction system in brown rot wood-decay fungi. Biotechnol Biofuels 10179 DOI: 10.1186/s13068-017-0865-2 (related highlight)SNS-HFIRSmall-Angle Neutron Scattering (SANS), Neutron Spectroscopy (NS)Goodell, B., Y. Zhu, S. Kim, K. Kafle, D. Eastwood, G. Daniel, J. Jellison, M. Yoshida, L. Groom, S.V. Pingali, and H. O'NeillModification of the nanostructure of lignocellulose cell walls via a non-enzymatic lignocellulose deconstruction system in brown rot wood-decay fungiBiotechnol Biofuels1017910.1186/s13068-017-0865-2
2017Herrmann, J., F. Jabbarpour, P.G. Bargar, J.F. Nomellini, P.N. Li, T.J. Lane, T.M. Weiss, J. Smit, L. Shapiro, and S. Wakatsuki. Environmental Calcium Controls Alternate Physical States of the Caulobacter Surface Layer. Biophys J 112(9) 1841-1851 DOI: 10.1016/j.bpj.2017.04.003 (related highlight)SSRLSmall-Angle X-Ray Scattering (SAXS)Herrmann, J., F. Jabbarpour, P.G. Bargar, J.F. Nomellini, P.N. Li, T.J. Lane, T.M. Weiss, J. Smit, L. Shapiro, and S. WakatsukiEnvironmental Calcium Controls Alternate Physical States of the Caulobacter Surface LayerBiophys J112(9)1841-185110.1016/j.bpj.2017.04.003
2017Hindt, M.N., G.Z. Akmakjian, K.L. Pivarski, T. Punshon, I. Baxter, D.E. Salt, and M.L. Guerinot. BRUTUS and its paralogs, BTS LIKE1 and BTS LIKE2, encode important negative regulators of the iron deficiency response in Arabidopsis thaliana. Metallomics 9(7) 876-890 DOI: 10.1039/c7mt00152e (related highlight)APS, NSLS-IIX-Ray Fluorescence Imaging Hindt, M.N., G.Z. Akmakjian, K.L. Pivarski, T. Punshon, I. Baxter, D.E. Salt, and M.L. GuerinotBRUTUS and its paralogs, BTS LIKE1 and BTS LIKE2, encode important negative regulators of the iron deficiency response in Arabidopsis thalianaMetallomics9(7)876-89010.1039/c7mt00152e
2017Kohler, A.C., M.J.L. Mills, P.D. Adams, B.A. Simmons, and K.L. Sale. Structure of aryl O-demethylase offers molecular insight into a catalytic tyrosine-dependent mechanism. Proc Natl Acad Sci U S A 114(16) E3205-E3214 DOI: 10.1073/pnas.1619263114 (related highlight)ALSX-Ray Macromolecular Crystallography (MC)Kohler, A.C., M.J.L. Mills, P.D. Adams, B.A. Simmons, and K.L. SaleStructure of aryl O-demethylase offers molecular insight into a catalytic tyrosine-dependent mechanismProc Natl Acad Sci U S A114(16)E3205-E321410.1073/pnas.1619263114
2017Michalska, K., G.C. Gucinski, F. Garza-Sanchez, P.M. Johnson, L.M. Stols, W.H. Eschenfeldt, G. Babnigg, D.A. Low, C.W. Goulding, A. Joachimiak, and C.S. Hayes. Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs. Nucleic Acids Res 45(17) 10306-10320 DOI: 10.1093/nar/gkx700 (related highlight)APSX-Ray Macromolecular Crystallography (MC)Michalska, K., G.C. Gucinski, F. Garza-Sanchez, P.M. Johnson, L.M. Stols, W.H. Eschenfeldt, G. Babnigg, D.A. Low, C.W. Goulding, A. Joachimiak, and C.S. HayesStructure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAsNucleic Acids Res45(17)10306-1032010.1093/nar/gkx700
2017Moissl-Eichinger, C., A.J. Probst, G. Birarda, A. Auerbach, K. Koskinen, P. Wolf, and H.N. Holman. Human age and skin physiology shape diversity and abundance of Archaea on skin. Sci Rep 7(1) 4039 DOI: 10.1038/s41598-017-04197-4 (related highlight)ALSInfrared (IR) ImagingMoissl-Eichinger, C., A.J. Probst, G. Birarda, A. Auerbach, K. Koskinen, P. Wolf, and H.N. HolmanHuman age and skin physiology shape diversity and abundance of Archaea on skinSci Rep7(1)403910.1038/s41598-017-04197-4
2017Mus, F., B.J. Eilers, A.B. Alleman, B.V. Kabasakal, J.N. Wells, J.W. Murray, B.P. Nocek, J.L. DuBois, and J.W. Peters. Structural Basis for the Mechanism of ATP-Dependent Acetone Carboxylation. Sci Rep 7(1) 7234 DOI: 10.1038/s41598-017-06973-8 (related highlight)APSX-Ray Macromolecular Crystallography (MC)Mus, F., B.J. Eilers, A.B. Alleman, B.V. Kabasakal, J.N. Wells, J.W. Murray, B.P. Nocek, J.L. DuBois, and J.W. PetersStructural Basis for the Mechanism of ATP-Dependent Acetone CarboxylationSci Rep7(1)723410.1038/s41598-017-06973-8
2017Nickels, J.D., S. Chatterjee, C.B. Stanley, S. Qian, X. Cheng, D.A.A. Myles, R.F. Standaert, J.G. Elkins, and J. Katsaras. The in vivo structure of biological membranes and evidence for lipid domains. PLoS Biol 15(5) e2002214 DOI: 10.1371/journal.pbio.2002214 (related highlight)SNS-HFIRSmall-Angle Neutron ScatteringNickels, J.D., S. Chatterjee, C.B. Stanley, S. Qian, X. Cheng, D.A.A. Myles, R.F. Standaert, J.G. Elkins, and J. KatsarasThe in vivo structure of biological membranes and evidence for lipid domainsPLoS Biol15(5)e200221410.1371/journal.pbio.2002214
2017Noel, V., K. Boye, J.S. Lezama Pacheco, S.E. Bone, N. Janot, E. Cardarelli, K.H. Williams, and J.R. Bargar. Redox Controls over the Stability of U(IV) in Floodplains of the Upper Colorado River Basin. Environ Sci Technol 51(19) 10954-10964 DOI: 10.1021/acs.est.7b02203 (related highlight)SSRLX-Ray Absorption SpectroscopyNoel, V., K. Boye, J.S. Lezama Pacheco, S.E. Bone, N. Janot, E. Cardarelli, K.H. Williams, and J.R. BargarRedox Controls over the Stability of U(IV) in Floodplains of the Upper Colorado River BasinEnviron Sci Technol51(19)10954-1096410.1021/acs.est.7b02203
2017Noel, V., K. Boye, R.K. Kukkadapu, S. Bone, J.S. Lezama Pacheco, E. Cardarelli, N. Janot, S. Fendorf, K.H. Williams, and J.R. Bargar. Understanding controls on redox processes in floodplain sediments of the Upper Colorado River Basin. Sci Total Environ 603-604663-675 DOI: 10.1016/j.scitotenv.2017.01.109 (related highlight)SSRLX-Ray Absorption SpectroscopyNoel, V., K. Boye, R.K. Kukkadapu, S. Bone, J.S. Lezama Pacheco, E. Cardarelli, N. Janot, S. Fendorf, K.H. Williams, and J.R. BargarUnderstanding controls on redox processes in floodplain sediments of the Upper Colorado River BasinSci Total Environ603-604663-67510.1016/j.scitotenv.2017.01.109
2017O'Dell, W.B., P.K. Agarwal, and F. Meilleur. Oxygen Activation at the Active Site of a Fungal Lytic Polysaccharide Monooxygenase. Angew Chem Int Ed Engl 56(3)767-770 DOI: 10.1002/anie.201610502 (related highlight)APS, SNS-HFIRX-Ray Macromolecular Crystallography (MC), Neutron Macromolecular Crystallography (MC)O'Dell, W.B., P.K. Agarwal, and F. MeilleurOxygen Activation at the Active Site of a Fungal Lytic Polysaccharide MonooxygenaseAngew Chem Int Ed Engl56(3)767-77010.1002/anie.201610502
2017O'Neill, H., S.V. Pingali, L. Petridis, J. He, E. Mamontov, L. Hong, V. Urban, B. Evans, P. Langan, J.C. Smith, and B.H. Davison. Dynamics of water bound to crystalline cellulose. Sci Rep 7(1) 11840 DOI: 10.1038/s41598-017-12035-w (related highlight)SNS-HFIRSmall-Angle Neutron Scattering (SANS), Neutron Spectroscopy (NS)O'Neill, H., S.V. Pingali, L. Petridis, J. He, E. Mamontov, L. Hong, V. Urban, B. Evans, P. Langan, J.C. Smith, and B.H. DavisonDynamics of water bound to crystalline celluloseSci Rep7(1)1184010.1038/s41598-017-12035-w
2017Oliver, R.C., S.V. Pingali, and V.S. Urban. Designing Mixed Detergent Micelles for Uniform Neutron Contrast. J Phys Chem Lett 8(20)5041-5046 DOI: 10.1021/acs.jpclett.7b02149 (related highlight)SNS-HFIRSmall-Angle Neutron Scattering (SANS)Oliver, R.C., S.V. Pingali, and V.S. UrbanDesigning Mixed Detergent Micelles for Uniform Neutron ContrastJ Phys Chem Lett8(20)5041-504610.1021/acs.jpclett.7b02149
2017Perticaroli, S., G. Ehlers, C.B. Stanley, E. Mamontov, H. O'Neill, Q. Zhang, X. Cheng, D.A. Myles, J. Katsaras, and J.D. Nickels. Description of Hydration Water in Protein (Green Fluorescent Protein) Solution. J Am Chem Soc 139(3) 1098-1105 DOI: 10.1021/jacs.6b08845 (related highlight)SNS-HFIRSmall-Angle Neutron Scattering (SANS)Perticaroli, S., G. Ehlers, C.B. Stanley, E. Mamontov, H. O'Neill, Q. Zhang, X. Cheng, D.A. Myles, J. Katsaras, and J.D. NickelsDescription of Hydration Water in Protein (Green Fluorescent Protein) SolutionJ Am Chem Soc139(3)1098-110510.1021/jacs.6b08845
2017Roth, M.S., S.J. Cokus, S.D. Gallaher, A. Walter, D. Lopez, E. Erickson, B. Endelman, D. Westcott, C.A. Larabell, S.S. Merchant, M. Pellegrini, and K.K. Niyogi. Chromosome-level genome assembly and transcriptome of the green alga Chromochloris zofingiensis illuminates astaxanthin production. Proc Natl Acad Sci U S A 114(21) E4296-E4305 DOI: 10.1073/pnas.1619928114 (related highlight)ALSX-Ray ImagingRoth, M.S., S.J. Cokus, S.D. Gallaher, A. Walter, D. Lopez, E. Erickson, B. Endelman, D. Westcott, C.A. Larabell, S.S. Merchant, M. Pellegrini, and K.K. NiyogiChromosome-level genome assembly and transcriptome of the green alga Chromochloris zofingiensis illuminates astaxanthin productionProc Natl Acad Sci U S A114(21)E4296-E430510.1073/pnas.1619928114
2017Schenck, C.A., C.K. Holland, M.R. Schneider, Y. Men, S.G. Lee, J.M. Jez, and H.A. Maeda. Molecular basis of the evolution of alternative tyrosine biosynthetic routes in plants. Nat Chem Biol 13(9) 1029-1035 DOI: 10.1038/nchembio.2414 (related highlight)APSX-Ray Macromolecular Crystallography (MC)Schenck, C.A., C.K. Holland, M.R. Schneider, Y. Men, S.G. Lee, J.M. Jez, and H.A. MaedaMolecular basis of the evolution of alternative tyrosine biosynthetic routes in plantsNat Chem Biol13(9)1029-103510.1038/nchembio.2414
2017Sutter, M., B. Greber, C. Aussignargues, and C.A. Kerfeld. Assembly principles and structure of a 6.5-MDa bacterial microcompartment shell. Science 356(6344) 1293-1297 DOI: 10.1126/science.aan3289 (related highlight)SSRLX-Ray Macromolecular Crystallography (MC)Sutter, M., B. Greber, C. Aussignargues, and C.A. KerfeldAssembly principles and structure of a 6.5-MDa bacterial microcompartment shellScience356(6344)1293-129710.1126/science.aan3289
2017Warren, C., T. Matsui, J.M. Karp, T. Onikubo, S. Cahill, M. Brenowitz, D. Cowburn, M. Girvin, and D. Shechter. Dynamic intramolecular regulation of the histone chaperone nucleoplasmin controls histone binding and release. Nat Commun 8(1) 2215 DOI: 10.1038/s41467-017-02308-3 (related highlight)SSRLSmall-Angle X-Ray Scattering (SAXS)Warren, C., T. Matsui, J.M. Karp, T. Onikubo, S. Cahill, M. Brenowitz, D. Cowburn, M. Girvin, and D. ShechterDynamic intramolecular regulation of the histone chaperone nucleoplasmin controls histone binding and releaseNat Commun8(1)221510.1038/s41467-017-02308-3
2017Wright, A.V., J.J. Liu, G.J. Knott, K.W. Doxzen, E. Nogales, and J.A. Doudna. Structures of the CRISPR genome integration complex. Science 357(6356) 1113-1118 DOI: 10.1126/science.aao0679 (related highlight)ALS, SSRLX-Ray Macromolecular Crystallography (MC), Small-Angle X-Ray Scattering (SAXS)Wright, A.V., J.J. Liu, G.J. Knott, K.W. Doxzen, E. Nogales, and J.A. DoudnaStructures of the CRISPR genome integration complexScience357(6356)1113-111810.1126/science.aao0679
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2017Xiao, X., H. Yang, V. Arutiunian, Y. Fang, G. Besse, C. Morimoto, B. Zirkle, and X.S. Chen. Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation. Nucleic Acids Research 45(12) 7494-7506 DOI: 10.1093/nar/gkx362ALS, APSX-Ray Macromolecular CrystallographyXiao, X., H. Yang, V. Arutiunian, Y. Fang, G. Besse, C. Morimoto, B. Zirkle, and X.S. ChenStructural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulationNucleic Acids Research45(12)7494-750610.1093/nar/gkx362
2017Yin, Z., M. Machius, E.J. Nestler, and G. Rudenko. Activator Protein-1 redox switch controlling structure and DNA-binding. Nucleic Acids Research 45(19) 11425-11436 DOI: 10.1093/nar/gkx795APSX-Ray Macromolecular CrystallographyYin, Z., M. Machius, E.J. Nestler, and G. RudenkoActivator Protein-1 redox switch controlling structure and DNA-bindingNucleic Acids Research45(19)11425-1143610.1093/nar/gkx795
2016Handing, K.B., I.G. Shabalin, O. Kassaar, S. Khazaipoul, C.A. Blindauer, A.J. Stewart, M. Chruszcz, and W. Minor. Circulatory zinc transport is controlled by distinct interdomain sites on mammalian albumins. Chem Sci 7(11) 6635-6648 DOI: 10.1039/c6sc02267g (related highlight)APSX-Ray Macromolecular Crystallography (MC)Handing, K.B., I.G. Shabalin, O. Kassaar, S. Khazaipoul, C.A. Blindauer, A.J. Stewart, M. Chruszcz, and W. MinorCirculatory zinc transport is controlled by distinct interdomain sites on mammalian albuminsChem Sci7(11)6635-664810.1039/c6sc02267g
2016Kober, D.L., J.M. Alexander-Brett, C.M. Karch, C. Cruchaga, M. Colonna, M.J. Holtzman, and T.J. Brett. Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms. Elife 5 DOI: 10.7554/eLife.20391 (related highlight)APSX-Ray Macromolecular Crystallography (MC)Kober, D.L., J.M. Alexander-Brett, C.M. Karch, C. Cruchaga, M. Colonna, M.J. Holtzman, and T.J. BrettNeurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanismsElife510.7554/eLife.20391
2016Lai, Y.T., G.L. Hura, K.N. Dyer, H.Y. Tang, J.A. Tainer, and T.O. Yeates. Designing and defining dynamic protein cage nanoassemblies in solution. Sci Adv 2(12) e1501855 DOI: 10.1126/sciadv.1501855 (related highlight)ALSSmall-Angle X-Ray Scattering (SAXS)Lai, Y.T., G.L. Hura, K.N. Dyer, H.Y. Tang, J.A. Tainer, and T.O. YeatesDesigning and defining dynamic protein cage nanoassemblies in solutionSci Adv2(12)e150185510.1126/sciadv.1501855
2016Le Gros, M.A., E.J. Clowney, A. Magklara, A. Yen, E. Markenscoff-Papadimitriou, B. Colquitt, M. Myllys, M. Kellis, S. Lomvardas, and C.A. Larabell. Soft X-Ray Tomography Reveals Gradual Chromatin Compaction and Reorganization during Neurogenesis In Vivo. Cell Rep 17(8) 2125-2136 DOI: 10.1016/j.celrep.2016.10.060 (related highlight)ALSX-Ray ImagingLe Gros, M.A., E.J. Clowney, A. Magklara, A. Yen, E. Markenscoff-Papadimitriou, B. Colquitt, M. Myllys, M. Kellis, S. Lomvardas, and C.A. LarabellSoft X-Ray Tomography Reveals Gradual Chromatin Compaction and Reorganization during Neurogenesis In VivoCell Rep17(8)2125-213610.1016/j.celrep.2016.10.060
2016McAndrew, R.P., N. Sathitsuksanoh, M.M. Mbughuni, R.A. Heins, J.H. Pereira, A. George, K.L. Sale, B.G. Fox, B.A. Simmons, and P.D. Adams. Structure and mechanism of NOV1, a resveratrol-cleaving dioxygenase. Proc Natl Acad Sci U S A 113(50) 14324-14329 DOI: 10.1073/pnas.1608917113 (related highlight)ALSX-Ray Macromolecular Crystallography (MC)McAndrew, R.P., N. Sathitsuksanoh, M.M. Mbughuni, R.A. Heins, J.H. Pereira, A. George, K.L. Sale, B.G. Fox, B.A. Simmons, and P.D. AdamsStructure and mechanism of NOV1, a resveratrol-cleaving dioxygenaseProc Natl Acad Sci U S A113(50)14324-1432910.1073/pnas.1608917113
2016Misasi, J., M. S.A. Gilman, M. Kanekiyo, M. Gui, A. Cagigi, S. Mulangu, D. Corti, J. E. Ledgerwood, A. Lanzavecchia, J. Cunningham, J. J. Muyembe-Tamfun, U. Baxa, B. S. Graham, Y. Xiang, N. J. Sullivan, and J. S. McLellan.. Structural and molecular basis for Ebola virus neutralization by protective human antibodies. Science. 351, 1343-1346. DOI: 10.1126/science.aad6117 (feature story)APSX-Ray Macromolecular Crystallography (MC)Misasi, J., M. S.A. Gilman, M. Kanekiyo, M. Gui, A. Cagigi, S. Mulangu, D. Corti, J. E. Ledgerwood, A. Lanzavecchia, J. Cunningham, J. J. Muyembe-Tamfun, U. Baxa, B. S. Graham, Y. Xiang, N. J. Sullivan, and J. S. McLellan.Structural and molecular basis for Ebola virus neutralization by protective human antibodies. Science351, 1343-1346.10.1126/science.aad6117
2016Muller, E. A., B. Pollard, H. A. Bechtel, P. van Blerkom, et al. Infrared vibrational nanocrystallography and nanoimaging. Science Advances 2(10), e1601006. DOI: 10.1126/sciadv.1601006 (feature story)ALSInfrared (IR) ImagingMuller, E. A., B. Pollard, H. A. Bechtel, P. van Blerkom, et alInfrared vibrational nanocrystallography and nanoimagingScience Advances2(10), e1601006.10.1126/sciadv.1601006
2016Vandavasi, V.G., D.K. Putnam, Q. Zhang, L. Petridis, W.T. Heller, B.T. Nixon, C.H. Haigler, U. Kalluri, L. Coates, P. Langan, J.C. Smith, J. Meiler, and H. O'Neill. A Structural Study of CESA1 Catalytic Domain of Arabidopsis Cellulose Synthesis Complex Evidence for CESA Trimers. Plant Physiol 170(1) 123-135 DOI: 10.1104/pp.15.01356 (related highlight)SNS-HFIR, NSLS-IISmall-Angle X-Ray Scattering (SAXS), Small-Angle Neutron Scattering (SANS)Vandavasi, V.G., D.K. Putnam, Q. Zhang, L. Petridis, W.T. Heller, B.T. Nixon, C.H. Haigler, U. Kalluri, L. Coates, P. Langan, J.C. Smith, J. Meiler, and H. O'NeillA Structural Study of CESA1 Catalytic Domain of Arabidopsis Cellulose Synthesis Complex Evidence for CESA TrimersPlant Physiol170(1)123-13510.1104/pp.15.01356
2016Zhu, X., A.P. Hitchcock, D.A. Bazylinski, P. Denes, J. Joseph, U. Lins, S. Marchesini, H.W. Shiu, T. Tyliszczak, and D.A. Shapiro. Measuring spectroscopy and magnetism of extracted and intracellular magnetosomes using soft X-ray ptychography. Proc Natl Acad Sci U S A 113(51) E8219-E8227 DOI: 10.1073/pnas.1610260114 (related highlight)ALSX-Ray Absorption and Emission Spectroscopy (XAS)Zhu, X., A.P. Hitchcock, D.A. Bazylinski, P. Denes, J. Joseph, U. Lins, S. Marchesini, H.W. Shiu, T. Tyliszczak, and D.A. ShapiroMeasuring spectroscopy and magnetism of extracted and intracellular magnetosomes using soft X-ray ptychographyProc Natl Acad Sci U S A113(51)E8219-E822710.1073/pnas.1610260114
2015Keiluweit, M., P. Nico, M.E. Harmon, J. Mao, J. Pett-Ridge, and M. Kleber. Long-term litter decomposition controlled by manganese redox cycling. Proc Natl Acad Sci U S A 112(38) E5253-5260 DOI: 10.1073/pnas.1508945112 (related highlight)ALS, SSRLX-Ray Absorption and Emission Spectroscopy (XAS), X-Ray ImagingKeiluweit, M., P. Nico, M.E. Harmon, J. Mao, J. Pett-Ridge, and M. KleberLong-term litter decomposition controlled by manganese redox cyclingProc Natl Acad Sci U S A112(38)E5253-526010.1073/pnas.1508945112
2015Keiluweit, M., P. Nico, M.E. Harmond, J. Maoe, et al. Long-term litter decomposition controlled by manganese redox cycling. Proceedings of the National Academies USA 12, E5253. DOI: 10.1073/pnas.1508945112 (feature story)ALSInfrared (IR) ImagingKeiluweit, M., P. Nico, M.E. Harmond, J. Maoe, et alLong-term litter decomposition controlled by manganese redox cyclingProceedings of the National Academies USA12, E5253.10.1073/pnas.1508945112
2015Luef, B., K. Frischkorn, K. Wrighton, et al. Diverse uncultivated ultra-small bacterial cells in groundwater. Nature Communications 6, 6372. DOI: 10.1038/ncomms7372 (feature story)ALSInfrared (IR) ImagingLuef, B., K. Frischkorn, K. Wrighton, et alDiverse uncultivated ultra-small bacterial cells in groundwaterNature Communications6, 6372.10.1038/ncomms7372
2015Michalska, K., A.D. Steen, G. Chhor, M. Endres, A.T. Webber, J. Bird, K.G. Lloyd, and A. Joachimiak. New aminopeptidase from 'microbial dark matter' archaeon. FASEB J 29(9) 4071-4079 DOI: 10.1096/fj.15-272906 (related highlight)APSX-Ray Macromolecular Crystallography (MC)Michalska, K., A.D. Steen, G. Chhor, M. Endres, A.T. Webber, J. Bird, K.G. Lloyd, and A. JoachimiakNew aminopeptidase from 'microbial dark matter' archaeonFASEB J29(9)4071-407910.1096/fj.15-272906
2015Sontz, P.A., J.B. Bailey, S. Ahn, and F.A. Tezcan. A Metal Organic Framework with Spherical Protein Nodes Rational Chemical Design of 3D Protein Crystals. J Am Chem Soc 137(36) 11598-11601 DOI: 10.1021/jacs.5b07463 (related highlight)SSRLX-Ray Macromolecular Crystallography (MC)Sontz, P.A., J.B. Bailey, S. Ahn, and F.A. TezcanA Metal Organic Framework with Spherical Protein Nodes Rational Chemical Design of 3D Protein CrystalsJ Am Chem Soc137(36)11598-1160110.1021/jacs.5b07463
2014Gross, E., X.-Z. Shu, S. Alayoglu, H A. Bechtel, et al. In situ IR and X-ray high spatial-resolution microspectroscopy measurements of multistep organic transformation in flow microreactor catalyzed by Au nanoclusters. J. Am. Chem. Soc. 136(9), 3624-3629. DOI: 10.1021/ja412740p (feature story)ALSInfrared (IR) ImagingGross, E., X.-Z. Shu, S. Alayoglu, H A. Bechtel, et alIn situ IR and X-ray high spatial-resolution microspectroscopy measurements of multistep organic transformation in flow microreactor catalyzed by Au nanoclusters.J. Am. Chem. Soc.136(9), 3624-3629.10.1021/ja412740p
2014Hans, A., E. Bechtel, A. Muller, L., Robert, et al. Ultrabroadband infrared nanospectroscopic imaging. PNAS 111(20), 7191-7196. DOI: 10.1073/pnas.1400502111 (feature story)ALSInfrared (IR) ImagingHans, A., E. Bechtel, A. Muller, L., Robert, et alUltrabroadband infrared nanospectroscopic imagingPNAS111(20), 7191-7196.10.1073/pnas.1400502111
2014Lai, Y.T., E. Reading, G.L. Hura, K.L. Tsai, A. Laganowsky, F.J. Asturias, J.A. Tainer, C.V. Robinson, and T.O. Yeates. Structure of a designed protein cage that self-assembles into a highly porous cube. Nat Chem 6(12)1065-1071 DOI: 10.1038/nchem.2107 (related highlight)ALSX-Ray Macromolecular Crystallography (MC), Small-Angle X-Ray Scattering (SAXS)Lai, Y.T., E. Reading, G.L. Hura, K.L. Tsai, A. Laganowsky, F.J. Asturias, J.A. Tainer, C.V. Robinson, and T.O. YeatesStructure of a designed protein cage that self-assembles into a highly porous cubeNat Chem6(12)1065-107110.1038/nchem.2107
2014Langan, P., L. Petridis, H. O'Neill, S.V. Pingali, M. Foston, Y. Nishiyama, R. Schulz, B. Lindner, B.L. Hanson, S. Harton, W. Heller, V. Urban, B. Evans, S. Gnanakaran, A.J. Ragauskas, J.C. Smith, and B. Davison. Common Processes Drive the Thermochemical Pretreatment of Lignocellulosic Biomass. Green Chemistry 1663-68 DOI: 10.1039/C3GC41962BSNS-HFIRSmall-Angle Neutron Scattering (SANS)Langan, P., L. Petridis, H. O'Neill, S.V. Pingali, M. Foston, Y. Nishiyama, R. Schulz, B. Lindner, B.L. Hanson, S. Harton, W. Heller, V. Urban, B. Evans, S. Gnanakaran, A.J. Ragauskas, J.C. Smith, and B. DavisonCommon Processes Drive the Thermochemical Pretreatment of Lignocellulosic BiomassGreen Chemistry1663-6810.1039/C3GC41962B
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2013Bornholdt, Z.A., T. Noda, D.M. Abelson, P. Halfmann, M.R. Wood, Y. Kawaoka, and E.O. Saphire. Structural rearrangement of ebola virus VP40 begets multiple functions in the virus life cycle. Cell 154(4) 763-774 DOI: 10.1016/j.cell.2013.07.015 (related highlight)SSRLX-Ray Macromolecular Crystallography (MC)Bornholdt, Z.A., T. Noda, D.M. Abelson, P. Halfmann, M.R. Wood, Y. Kawaoka, and E.O. SaphireStructural rearrangement of ebola virus VP40 begets multiple functions in the virus life cycleCell154(4)763-77410.1016/j.cell.2013.07.015
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2013Chao, F.A., A. Morelli, J.C. Haugner, 3rd, L. Churchfield, L.N. Hagmann, L. Shi, L.R. Masterson, R. Sarangi, G. Veglia, and B. Seelig. Structure and dynamics of a primordial catalytic fold generated by in vitro evolution. Nat Chem Biol 9(2) 81-83 DOI: 10.1038/nchembio.1138 (related highlight)SSRLX-Ray Absorption and Emission Spectroscopy (XAS)Chao, F.A., A. Morelli, J.C. Haugner, 3rd, L. Churchfield, L.N. Hagmann, L. Shi, L.R. Masterson, R. Sarangi, G. Veglia, and B. SeeligStructure and dynamics of a primordial catalytic fold generated by in vitro evolutionNat Chem Biol9(2)81-8310.1038/nchembio.1138
2013Heberle, F.A., R.S. Petruzielo, J. Pan, P. Drazba, N. Kucerka, R.F. Standaert, G.W. Feigenson, and J. Katsaras. Bilayer thickness mismatch controls domain size in model membranes. J Am Chem Soc 135(18) 6853-6859 DOI: 10.1021/ja3113615 (related highlight)SNS-HFIRSmall-Angle X-Ray Scattering (SAXS)Heberle, F.A., R.S. Petruzielo, J. Pan, P. Drazba, N. Kucerka, R.F. Standaert, G.W. Feigenson, and J. KatsarasBilayer thickness mismatch controls domain size in model membranesJ Am Chem Soc135(18)6853-685910.1021/ja3113615
2013Michalska, K., K. Tan, H. Li, C. Hatzos-Skintges, J. Bearden, G. Babnigg, and A. Joachimiak. GH1-family 6-P-beta-glucosidases from human microbiome lactic acid bacteria. Acta Crystallogr D Biol Crystallogr 69(Pt 3) 451-463 DOI: 10.1107/S0907444912049608 (related highlight)APSX-Ray Macromolecular Crystallography (MC)Michalska, K., K. Tan, H. Li, C. Hatzos-Skintges, J. Bearden, G. Babnigg, and A. JoachimiakGH1-family 6-P-beta-glucosidases from human microbiome lactic acid bacteriaActa Crystallogr D Biol Crystallogr69(Pt 3)451-46310.1107/S0907444912049608
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2012Chen, L., H.-Y. N. Holman, Z. Hao, H. A. Bechtel, et al. Synchrotron infrared measurements of protein phosphorylation in living single PC12 cells during neuronal differentiation. Analytical Chemistry 84(9), 4118-4125. DOI: 10.1021/ac300308x (feature story)ALSInfrared (IR) ImagingChen, L., H.-Y. N. Holman, Z. Hao, H. A. Bechtel, et alSynchrotron infrared measurements of protein phosphorylation in living single PC12 cells during neuronal differentiationAnalytical Chemistry84(9), 4118-4125.10.1021/ac300308x
2012Westfall, C.S., C. Zubieta, J. Herrmann, U. Kapp, M.H. Nanao, and J.M. Jez. Structural basis for prereceptor modulation of plant hormones by GH3 proteins. Science 336(6089) 1708-1711 DOI: 10.1126/science.1221863 (related highlight)APSX-Ray Macromolecular Crystallography (MC)Westfall, C.S., C. Zubieta, J. Herrmann, U. Kapp, M.H. Nanao, and J.M. JezStructural basis for prereceptor modulation of plant hormones by GH3 proteinsScience336(6089)1708-171110.1126/science.1221863
2010Hazen, T. C., E. A. Dubinsky, T. Z. DeSantis, G. L. Andersen, et al. Deep-sea oil plume enriches indigenous oil-degrading bacteria. Science 330(6001), 204-208. DOI: 10.1126/science.1195979 (feature story)ALSInfrared (IR) ImagingHazen, T. C., E. A. Dubinsky, T. Z. DeSantis, G. L. Andersen, et alDeep-sea oil plume enriches indigenous oil-degrading bacteriaScience330(6001), 204-208.10.1126/science.1195979
2009Holman, H.-Y., R. Miles, Z. Hao, E. Wozel, et al. Real-time chemical imaging of bacterial activity in biofilms using open-channel microfluidics and synchrotron FTIR spectromicroscopy. Analytical Chemistry 81(20), 8564-8570. DOI: 10.1021/ac9015424 (feature story)ALSInfrared (IR) ImagingHolman, H.-Y., R. Miles, Z. Hao, E. Wozel, et alReal-time chemical imaging of bacterial activity in biofilms using open-channel microfluidics and synchrotron FTIR spectromicroscopyAnalytical Chemistry81(20), 8564-8570.10.1021/ac9015424