Unelectrified Aerosol-Producing Device for Biological Studies
The novel device has the potential to impact many fields of basic and applied research including structural biology, carbon capture, and climate science. Microdroplet production can also benefit sample environment instrumentation such as mass spectrometry, X-ray free-electron lasers (XFELs), synchrotrons, and cryo-electron microscopy (cryo-EM) used in, for example, biomacromolecule characterization.
This work has been supported by the Cluster of Excellence “The Hamburg Center for Ultrafast Imaging – Structure, Dynamics and Control of Matter at the Atomic Scale” of the Deutsche Forschungsgemeinschaft (CUI, DFG-EXC1074, project ID 194651731). This work was conducted through the Berkeley Synchrotron Infrared Structural Biology (BSISB) Imaging program, supported by the U.S. Department of Energy, Office of Biological and Environmental Research, under contract no. DE-AC02-05CH11231. This work was performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under contract DE-AC52-07NA27344. The authors would like to acknowledge the cleanroom facility provided by the Center for Free-Electron Laser Science (CFEL) at Deutsches Elektronen-Synchrotron (DESY).
- BER Resource: Berkeley Synchrotron Infrared Structural Biology
- BSISB News: Aerosol ‘Whipping Jet’ Technology Is First of Its Kind
- LBNL News: Whip It: Novel Liquid Jet Makes Droplets March to the Beat
Narayanasamy et al. 2023. A sui generis whipping instability based self-sequencing multi-monodisperse 2D Sprays from an anisotropic microfluidic liquid jet device. Cell Reports Physical Science, 4(1), 101221. [DOI: 10.1016/j.xcrp.2022.101221]