Researchers successfully capped 7 years of work by obtaining a high-resolution (2.2 Å) structure of the membrane protein at the heart of the photosynthetic RC of H. modesticaldum. The structure revealed details such as the interactions between light-harvesting “antenna” molecules and the electron-transfer chain, where the initial steps required to convert photon energy into chemical energy occurs. With this data, the research team was able to make comparisons to other types of RCs, gaining new perspectives on the early evolution of photosynthesis and how nature optimized light-driven energy collection. This work will help unlock the secrets of photosynthesis, possibly leading to the development of cleaner, solar-based renewable energy.
Gisriel, C., et al. “Structure of a Symmetric Photosynthetic Reaction Center–Photosystem.” Science 357(6355), 1021–1025 (2017). [DOI:10.1126/science.aan5611].
Instruments and Facilities: Beamline 8.2.1 at Advanced Light Source at Lawrence Berkeley National Laboratory; Advanced Photon Source at Argonne National Laboratory.
Funding Acknowledgements: Work funded by the Division of Chemical Sciences, Geosciences, and Biosciences, Office of Basic Energy Sciences (OBES), U.S. Department of Energy (DOE) Office of Science, through grant DE-SC0010575 to K.E.R., R.F., and J.H.G. and supported with x-ray crystallographic equipment and infrastructure provided by P. Fromme of the Biodesign Center for Applied Structural Discovery at Arizona State University. Berkeley Center for Structural Biology supported in part by National Institutes of Health’s (NIH) National Institute of General Medical Sciences (NIGMS) and Howard Hughes Medical Institute (HHMI). The Advanced Light Source (ALS) is a DOE Scientific User Facility supported by OBES, Director, DOE Office of Science, and operated for DOE Office of Science by Lawrence Berkeley National Laboratory (LBNL). Results derived from work performed at Argonne National Laboratory’s (ANL) Structural Biology Center (SBC) at the Advanced Photon Source (APS). SBC funded by the Office of Biological and Environmental Research (OBER), DOE Office of Science. ANL is operated by University of Chicago Argonne, LLC, for the DOE Office of Science under contract DE-AC02-06CH11357.